Showing posts with label health benefits. Show all posts
Showing posts with label health benefits. Show all posts

Thursday, May 26, 2011

Physical Exercises may Delay or even Reverse Alzheimer’s Disease Symptoms

Scientists have discovered an interesting link between fitness exercises bring ultimately positive impact on the well-being of the Alzheimer’s patient, being able to slow down and even slightly reverse the symptoms severity.  Keeping your body fit causes multiple positive changes to your physical, emotional, and mental health, so there is an overwhelming reasons to include the daily routine in your action plan to fight Alzheimer’s disease.

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Patients with early Alzheimer's disease who exercised regularly saw less deterioration in areas of the brain that control memory, according to a study released at the 2008 International Conference on Alzheimer's Disease.

Mild Alzheimer's disease patients with higher physical fitness had larger brains compared to mild Alzheimer's patients with lower physical fitness, according to a study published in the July 15, 2008, issue of Neurology, the medical journal of the American Academy of Neurology.

For the Alzheimers and exercise study, 121 people age 60 and older underwent fitness tests using a treadmill as well as brain scans to measure the white matter, gray matter and total volume of their brains. Of the group, 57 were in the early stages of Alzheimer's disease while the rest of the group did not have dementia.

"People with early Alzheimer's disease who were less physically fit had four times more brain shrinkage when compared to normal older adults than those who were more physically fit, suggesting less brain shrinkage related to the Alzheimer's disease process in those with higher fitness levels," said study author Jeffrey M. Burns, MD, of the University of Kansas School of Medicine in Kansas City and member of the American Academy of Neurology.

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The results of this Alzheimers and exercise study remained the same regardless of age, gender, and severity of dementia, physical activity and frailty.

"People with early Alzheimer's disease may be able to preserve their brain function for a longer period of time by exercising regularly and potentially reducing the amount of brain volume lost.

Evidence shows decreasing brain volume is tied to poorer cognitive performance, so preserving more brain volume may translate into better cognitive performance," Burns said. "This is one of the first studies to explore the relationship between Alzheimers and exercise (cardio respiratory fitness)”.

The positive message from researchers is that in order to benefit mental activity, physical activity does not necessarily need to be extremely strenuous or constitute a big time commitment. The major point is that although moderate exercise can benefit mental capacity, it is necessary that it be done on a consistent basis.

By strengthening the heart, exercise increases blood flow to the brain, which increases tolerance to exercise, prunes body weight, and lowers blood pressure. In addition, exercise lowers the bad cholesterol (LDL) and raises good cholesterol (HDL) with the added benefit of increasing sensitivity to insulin, which reduces likelihood of developing a disease that could negatively affect brain function.

Older adults exhibiting early signs of Alzheimer's disease can help prevent mental decline through high-intensity aerobic exercise, according to another study published in the Jan. 11, 2010 edition of the journal "Archives of Neurology." A team led by Laura Baker observed the effects of aerobic training on 33 older adults diagnosed with mild-cognitive impairment. For six months, subjects either participated in high-intensity aerobic exercises or completed stretching activities. The aerobic group demonstrated significant gains in mental agility, when compared to the stretching group, which continued to decline. Baker reports that aerobic exercise likely protects the brain by building heart and artery resilience --- increasing blood flow to the brain.

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Mild Exercise Probed as a Means to Counter Dementia

Modest physical activity, which ranges from around thirty minutes a day, is recommended. If there are any health issues or concerns, then it is highly recommended that a professional health care advocate be consulted prior to beginning any new exercise regimen.

Need help with the arrangements – involve your caregiver or family member. Be consistent, and you will see positive results for your overall well-being soon.

So what types of activities are recommended?

Walking is the number one recommended activity.  It is a low impact activity that can be started slowly and gradually increased to achieve greater intensity and longer durations.  Daily changes can be made in an outdoor or indoor walking routine (e.g., many people vigorously walk in malls during inclement weather) to keep interest high (which assists in maintaining motivational levels).

Light strength training can be performed from a wheelchair.  Studies have shown that individuals who perform strength training will also improve bone density. Tai chi is an excellent activity for strength, balance and coordination.

Aerobic exercises that have low impact are highly recommended. These include swimming (even walking in waist deep water will build strength, as will walking in deep sand) and bicycling.
Gentle forms of yoga emphasizing mild stretching exercises improve circulation, digestion and focus.

Note that exercise is natural and lacks the unpleasant and dangerous side effects associated with most, if not all, prescription drugs.

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Sample of the Physical Fitness Training Protocol

  1. Weigh in. Note your weight at the beginning of the training session.
  2. Check Pulse.  This is obtained after several minutes of sitting quietly after arriving to the Fitness Center.  Do not proceed if your resting pulse is higher than 90.
  3. Warm-up Walk.  Walk on spot for several minutes to warm up.
  4. Stretches.  Perform a series of stretches, most of which are done sitting down: Neck stretch, (right, left, forward); arm across chest (r & l); hamstring stretch: sit, extend legs, one bent, one straight. Slide arms down straight leg, head looking forward, then switch.  calf stretch (r & l). Do each stretch twice. Hold for 16 seconds.
  5. Calf raise.  Up on tip toes and down, holding lightly onto bar.  Repeat 15 times. 
  6. Step up on Reebok step aerobics box and down (without bringing other leg to rest on box) – right, then left.  One set per side. Add 2 reps per week.
  7. Balance practice: Stand on box on right foot, holding onto bar lightly. Signal to the instructor when ready to let go and count seconds held; do 3 times for each foot and record longest time.
  8. Wrist roll-ups.  Perform two sets (each set = one rolling up of rope and one unrolling).
  9. Treadmill.  Fasten safety clip.  Set elevation at 0 and rate at 1.0 or more, depending on your physical abilities.

You should be at 15-20 minutes from the beginning of exercises by now.
 
  1. Bike.  Adjust seat height and position to be comfortable. Enter weight. Use up and down arrows to set weight and time. Hit start.
  2. Weight training. Perform 2 sets of 10-12 reps on 5 different machines that work large muscle groupsRest for at least 30 seconds after each set.  After two successful workouts of 2 sets of 10 at a given weight, increase to 12 reps. Then increase weight – 2-6 pounds, as tolerated, for upper body machine; 10-20 pounds for leg press. If you feel you are working too hard, drop back.
  3. Leg Press.  Strengthens muscles of the legs and buttocks. Back should be in most upright position possible. Shoulder pads should just touch shoulders. Legs, when on plate, should be at about 6 inches apart and at 90 degree angle (slightly greater than 90 for subjects with knee problems.
  4. Chest Press. Strengthens muscles of the chest and shouldersTwo adjustments: back and seat. Back should be so that vertical sidebar is parallel to your shoulder and upper arm when you are leaning back.  Seat height should be so that crook of arm handle is at armpit level.  Ankles should be crossed.
  5. Row: Strengthens muscles of the arm shoulder, and upper torso. One adjustment. Adjust seat so that center padded column is against your stomach, but you are sitting up straight, not slouched over the pad.  Move yourself as close to hand grips as possible.
  6. Torso Arm: Strengthens muscles of the arm, shoulder, and upper torso.  Back in upright position, adjustable seat height. Seat is raised in order for you to reach hand grips. If uncomfortable high off the ground, grips can be lowered. Use seat belt.
  7. Overhead Press: Strengthens chest and shoulder muscles.  Adjust seat so that your shoulder is at the crook of the hand grip.  Ankles should be crossed. Use seat belt. 

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You should be at 30-40 minutes from the beginning of exercises by now. Some general notes:
  1. Drink plenty of water through the exercise.
  2. Accept help from your family member or personal trainer to supervise your activity and monitor your vitals.
  3. Be reasonable. You have a life marathon to run, do not get yourself exhausted on the first mile.
  4. Be patient, do not expect magic improvements overnight.
  5. Reward yourself for being consistent.

 Sources and Additional Information:



Saturday, February 20, 2010

Ginger as Natural Remedy for Alzheimer's and some Other Diseases

Not only is ginger (Zingiber officinale) one of the most popular of all the spices but is also of the top five antioxidant foods (American Journal of Clinical Nutrition, July 2006). Numerous studies investigating ginger's medicinal properties have also shown it to be effective in conditions such as motion sickness and the prevention and treatment of diseases such as Alzheimer's disease, cancer, cardiovascular disease, diabetes, inflammatory diseases and stomach ulcers.

How Ginger Fights Alzheimer’s?
Two of ginger's most important antioxidants, curcumin and gingerol, have been shown to inhibit and even reverse the deposition in the brain of the amyloid plaques that are associated with Alzheimer's disease. Moreover, zingerone, another of ginger's antioxidants, neutralizes the powerful oxidant, peroxynitrite, which has also been implicated as an aggravating factor in Alzheimer's and other neurodegenerative diseases.

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American Botanical Council Study (2003)
Fibrillar beta-amyloid peptide is prevalent in brains of people with Alzheimer's disease. Beta-amyloid peptide causes microglial cells (cells in the brain that provide support) to increase production of cytokines and chemokines. Cytokines and chemokines are substances in the body that promote inflammation. Some hypotheses state that inflammation plays a key role in the pathogenesis of Alzheimer's disease. Ginger (Zingiber officinale) has anti-inflammatory properties. The purpose of this study was to determine whether a ginger extract could dampen the induction of inflammation-related genes in human THP-1 cells exposed to lipopolysaccharide (LPS), proinflammatory, cytokines, and fibrillar amyloid peptide Abeta(1-42), a major component of neuritic plaques.

As expected, the proinflammatory mediators caused upregulation of inflammatory markers. The ginger extract had a broad inhibitory effect on cytokine and beta-amyloid peptide induced expression of inflammation-related genes in activated THP-1 cells. The extract inhibited the induction of genes involved in the inflammatory cascade (TNF-alpha, IL-1beta, MCP-1, MIP-1alpha, IP-10, and COX2). The ginger extract has a mechanism of action that is different from that of nonsteroidal anti-inflammatory drugs. 

The authors of the research conclude that this ginger extract may help prevent the sustained elevation of the proinflammatory cytokines, as would be seen in people with Alzheimer's disease. The authors believe that the ginger extract offers a promising and safe treatment to protect against the harmful effects of chronic microglial cell-associated inflammation in Alzheimer's disease. 

General Ginger Usefulness
Ginger is a good source of antioxidants. Antioxidants help rid the body of free radicals and boost the immune system, helping fight off infectious diseases like the cold and flu. Consuming antioxidants may also help prevent diseases such as cancer, heart disease, and arthritis. Ginger is also used to treat stomach aches, nausea, and diarrhea.
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Dosage
I personally prefer making the ginger hot mix with lemon and honey, which is, besides being an excellent immune booster, very tasty. However, there are some people who cannot stand the specific ginger taste. For them, the preferable solution would be ginger pills and crystals.

There are no definitive dosing guidelines, but if you want to take a powdered ginger extract in capsules, a minimum dose, recommended by Robert Pendergrast, MD, would be 250mg four times daily (with meals and bedtime). If you like the crystallized ginger, one cube is probably 1000 mg of ginger, and one or two a day would be a good dose.

Ginger Side Effects, Interactions and Warnings
In general, ginger appears to be safe. Side effects of ginger were not reported in most
studies. A study of healthy subjects reports no severe ginger side effects, based on
biochemistry data. While studies of treating nausea and vomiting or of cancer patients
reported ginger side effects and the side effects are gastrointestinal disturbance, sleepiness, restless, sedation and heartburn. Finally, ginger may interact with surgical medications including anesthesia, leading to arrhythmias, poor wound healing, bleeding, photosensitivity reaction, and prolonged sedation. Ginger may also interact with certain anticoagulants and analgesics to cause bleeding.

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