There are multiple studies, published recently, claiming
that oxidative stress plays a significant role in the progression of multiple
diseases, including diabetes, Alzheimer disease (AD), and atherosclerosis.
Oxidative stress generally results from an imbalance between free radicals
generated during normal cellular metabolism and the free radical or oxidant
scavenging capacity of the endogenous antioxidant enzymes.
Although attempts at neutralization Oxidative stress of
Alzheimer's of free radicals with dietary antioxidant supplements have been
reported to have certain positive effects, there are also conflicting reports
placing the suggestions on the positive antioxidants’ effects in the grey area
of the Alzheimer’s alternative therapies need further validation.
Yes, oxidative stress is actually positively cause neurons
in the brain to die, resulting in Alzheimer’s. James Franklin, an associate
professor of pharmaceutical and biomedical sciences, has studied neuronal cell
death and oxidative stress at UGA since 2004. “The brain consumes 20 percent of
the oxygen in the body even though it only makes up 5 percent of the volume, so
it’s particularly susceptible to oxidative stress,” said Franklin. He hypothesized
that antioxidants administered unsuccessfully by other researchers to treat
Alzheimer’s were not concentrated enough in the mitochondria of cells.
Mitochondria are structures within cells that have many functions, including
producing oxidative molecules that damage the brain and cause cell death.
Much attention has been focused recently on naturally
occurring polyphenolic compounds that are capable of inducing antioxidant
enzymes. Prevention of oxidative stress by phytochemicals has evolved as a
promising therapeutic approach in the treatment of several diseases. There is a
dietary supplement designed to induce endogenous antioxidant enzymes. It
consists of five herbal ingredients, namely, silymarin from milk thistle
(Silibum marianum), bacopa (Bacopa monniera) extract, ashwagandha (Withania
somnifera), green tea (Camilia sinesis) extract, and curcumin from turmeric (Curcuma
longa). The therapeutic properties of each of these herbs have been previously
reported. However, to gain optimal beneficial effects, to help with Oxidative
Stress with Alzheimer's the individual components may have to be used at
pharmacological doses not easily achieved by oral administration and that could
cause toxic side effects. Therefore, this all natural product formulated with
the concept of combining multiple phytochemicals at low doses to gain synergy
among them.
Note that none of the individual components is known to have
any significant clinical benefit from antioxidant effects. Some of them are
listed in the Natural Medicines Comprehensive Database as “not enough
information” to know if they are safe. One has estrogenic properties and more
than one has known side effects and potential interactions with other drugs.
The only one that even sounds remotely like it might have some pertinent data
behind it is green tea. Green tea contains antioxidant catechins that are
“thought to possibly have a protective effect against atherosclerosis and heart
disease” and contains flavonoids that “might reduce lipoprotein oxidation;
however benefits have not yet been described in humans.”
Therefore, it is all about combination of these components
in one natural substance – Protandim.
Protandim is claimed
to be more than one million times more effective at getting rid of free
radicals than standard anti-oxidants. How is this possible?
Anti-oxidants generally get rid of free radicals one-to-one, meaning one
molecule of an anti-oxidant gets rid of one molecule of a free radical. But
Protandim works in an entirely different way. It "turns on" an enzyme
in the body: Superoxide Dismutase (SOD). This enzyme is a scavenger of free
radicals and one SOD enzyme can
neutralize up to one-million free
radicals every second for up to
13 days!!!
Dr. Joe McCord, PhD, who discovered the SOD enzyme, also
discovered the formula for Protandim. It includes several totally natural
products, which individually do not turn on SOD, but collectively they do turn
on the SOD enzyme.
As developers claim,
the formula is so powerful, that you would need to consume the nutrients below
to equal one pill of Protandim:
- Eat 375 Oranges Daily
- Drink 87 Glasses of Red Wine Daily
- Eat 31 Pounds of Strawberries Daily
- Eat 32 Pounds of Raspberries Daily
The dose is 2 pills a day for the first month. In the second
and future months take one pill a day if you are healthy, or take two pills a
day if you have a chronic illness. No undesirable side effects have been
reported.
General alleged Protadim benefits include:
- Boosts immune system.
- Promotes cardiovascular health by lowering oxidative stress.
- Only product that reduces cell aging.
- Helps to fight oxidative stress and aging.
- It is 100% safe free from all banned substances.
- It is patented formula, which is the result of decades of research by professionals.
- The ingredients used are all natural. It has a shelf life of three years.
- Protandim is a Supplement with a scientifically proved formula, can deliver more antioxidants than conventional supplements or vitamins.
Sources and Additional
Information: